Keywords
screening program
body
cardia
antrum
How to Cite
Abstract
Introduction: Despite the ongoing decline in incidence, stomach cancer remains one of the most common and deadly tumors worldwide. According to the literature, stomach cancer is the third leading cause of cancer-related deaths globally, ranking behind lung cancer and colorectal cancer. This global impact underscores the significance of our research. About 1 in 12 cancer deaths can be attributed to stomach cancer, which has the highest incidence among all cancers, with over one million new cases diagnosed each year worldwide.
Our primary objectives in this study were to provide evidence and a detailed statistical description of the demographic, diagnostic, clinical, and pathological data of stomach cancer patients included in this study. These patients were hospitalized in two clinical surgery medical centers during the period from January 2009 to January 2019: the University Clinical Center in Pristina, Department of Surgery, and the Regional Hospital in Ferizaj, Department of Surgery.
Material and Methods: The study included 115 patients who met the criteria, and the Study variables were obtained from clinical record data that include: Gender (Male, Female); Age; Clinic of the disease: (indigestion Weakness, Weight loss, anorexia, Melena, Abdominal pain, Epigastric pain, Vomiting…); Tumor stage, histopathologic and lesion type.
Results: Stomach cancer affects both genders, with a preference for men, with a ratio of 1.4/1 (M: F). The most affected age group is 51-70 years, which includes about 61.3% of patients. Depending on the localization of gastric cancer, the most affected part of our study was the body of the stomach (46%), the antral part 38%, and the cardia part 15.7%. Typical symptoms in our patients included: Indigestion 46 (40%); Loss of appetite 41 (35.6%); Abdominal pain 70(60.8%); Nausea/ vomiting 35(30.4%);
Conclusions: This study underscores the importance of early detection in the management of gastric cancer in Kosovo. The findings highlight the need for timely diagnosis and management, especially in high-risk age groups. We hope that this emphasis on early detection will help in reducing the burden of stomach cancer in our population.
References
Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018; 68: 394-424.
Ferlay J, Ervik M, Lam F, et al. Global Cancer Observatory: Cancer Today. Lyon, France: International Agency for Research on Cancer. Available from: https://gco.iarc.fr/today, Accessed 09 October 2018. In. 2018
World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR). Continuous Update Project Report: Diet, Nutrition, Physical Activity and Stomach Cancer 2016. Revised 2018. London: World Cancer Research Fund International; 2018.
Balakrishnan M, George R, Sharma A, Graham DY. Changing trends in stomach cancer throughout the world. Curr Gastroenterol Rep 2017; 19: 36.
Mukaisho K, Nakayama T, Hagiwara T, et al. Two distinct etiologies of gastric cardia adenocarcinoma: interactions among pH, Helicobacter pylori, and bile acids. Front Microbiol 2015; 6: 412.
Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histoclinical classification. Acta Pathol Microbiol Scand 1965; 64: 31-49.
Yaghoobi M, Bijarchi R, Narod SA. Family history and the risk of gastric cancer. Brit J Can2010;102:237-42.
Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015; 65(2): 87– 108.
Japanese Gastric Cancer Association. Japanese classification of gastric carcinoma: 3rd English edition. Gastric Cancer. 2011;14( 2): 101– 12.
A. A. Julian and C. W. Timothy, “Adenocarcinoma and other tumors of the stomach,” in Sleisenger and Fordtrean’s Gastrointestinal and Liver Disease, M. Feldman, L. S. Friedman, and L. J. Brandt, Eds., Elsevier Saunders, Philadelphia, Pa, USA, 9th edition, 2010.
W. J. Blot, S. S. Devesa, R. W. Kneller, and J. F. Fraumeni Jr.,“Rising incidence of adenocarcinoma of the esophagus and gastric cardia,” The Journal of the AmericanMedical Association, vol. 265, no. 10, pp. 1287–1289, 1991.
J. R. Kelley and J. M. Duggan, “Gastric cancer epidemiology and risk factors,” Journal of Clinical Epidemiology, vol. 56, no. 1, pp.1–9, 2003.
M. A. Qurieshi, M. A. Masoodi, S. A. Kadla, S. Z. Ahmad, and P. Gangadharan, “Gastric cancer in Kashmir,” Asian Pacific Journal of Cancer Prevention, vol. 12, no. 1, pp. 303–307, 2011.
M. A. Kabir, R. Barua, H. Masud et al., “Clinical presentation, histological findings and prevalence of Helicobacter pylori in patients of gastric carcinoma,” FaridpurMedical College Journal, vol. 6, pp. 78–81, 2011.
S. Kaneko and T. Yoshimura, “Time trend analysis of gastric cancer incidence in Japan by histological types, 1975–1989,” British Journal of Cancer, vol. 84, no. 3, pp. 400–405, 2001.
J. Parsonnet, D. Vandersteen, J. Goates, R. K. Sibley, J. Pritikin, and Y. Chang, “Helicobacter pylori infection in intestinal- and diffuse-type gastric adenocarcinomas,” Journal of the National Cancer Institute, vol. 83, no. 9, pp. 640–643, 1991.
K. D. Crew and A. I. Neugut, “Epidemiology of gastric cancer,”World Journal of Gastroenterology, vol. 12, no. 3, pp. 354–362, 2006.
S. W. Hwang, D. H. Lee, S. H. Lee et al., “Preoperative staging of gastric cancer by endoscopic ultrasonography and multidetector-row computed tomography,” Journal of Gastroenterology and Hepatology, vol. 25, no. 3, pp. 512–518, 2010.
S. P. Afridi, F. Bano, and S.-U. Shafiq-ur-Rahman, “Pattern and presentation of carcinoma stomach,” Journal of the College of Physicians and Surgeons Pakistan, vol. 21, no. 3, pp. 161–163, 2011.
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