Abstract
Introduction: Significant variations in incidence rates have been observed in the analysis of anecdotal Pilonidal Sinus Disease (PSD) incidents worldwide.
Objective: This study examines the accuracy of PSD incidence estimates and the variations associated with study size from 1833 to the present.
Material and Methods: A comprehensive search was conducted in global literature databases, including PubMed, Embase, Science Direct, and others, to gather any PSD incidence data reported between 1833 and 2023.
Results: The study sizes ranged from 26 to 82,217,837 individuals, with incidence rates varying from 8 to 30,000 cases per 100,000 persons. Notably, in study populations below 200,000 individuals, the incidence rate ranged from 8 to 30,000 cases per 100,000 persons. However, this range narrowed when studying populations exceeding 200,000 persons, with incidence rates ranging from 7 to 300 cases per 100,000 persons.
Limitations: No limitations were identified in this study.
Conclusion: The findings suggest reliable PSD incidences can be calculated with study populations exceeding 200,000 individuals. In such cases, the variability of incidence rates decreases as study size increases, although other known and unknown factors continue to influence the outcomes.
References
Associaton WM. WMA Declaration of Helsinki - Ethical Principles for Medical Research Involving Human Subjects. 1964. http://www.wma.net/en/30publications/10policies/b3/.
Evers T, Doll D, Matevossian E, et al. Trends in incidence and long-term recurrence rate of pilonidal sinus disease and analysis of associated influencing factors. Zhonghua wai ke za zhi [Chinese journal of surgery] 2011; 49(9): 799-803.
Oetzmann von Sochaczewski C, Godeke J. Pilonidal sinus disease on the rise: a one-third incidence increase in inpatients in 13 years with substantial regional variation in Germany. Int J Colorectal Dis 2021; 36(10): 2135-45.
Luedi MM, Schober P, Stauffer VK, Diekmann M, Doll D. Global Gender Differences in Pilonidal Sinus Disease: A Random-Effects Meta-Analysis. World J Surg 2020; 44(11): 3702–9.
Chijiwa T, Suganuma T, Takigawa T, et al. Pilonidal sinus in Japan maritime self-defense force at Yokosuka. Mil Med 2006; 171(7): 650-2.
Luedi MM, Schober P, Stauffer VK, Diekmann M, Andereggen L, Doll D. Gender-specific prevalence of pilonidal sinus disease over time: A systematic review and meta-analysis. ANZ J Surg 2021; 91(7-8): 1582-7.
Doll D, Stauffer V, Diekann M, Van Wyk P, Luedi MM. Turkey is leading in the 21(st) century pilonidal sinus disease research. Turk J Surg 2020; 36(3): 284-90.
Heurtaux A. Infundibulum coccygien et fistules para-coccygienne. Soc de chirurgie 1882.
Wette T. Über Fisteln und Geschwülste in der Sakrokokzygealgegend. Dermoid im Sakralkanale. Arch f klin Chir 1894; 47(47): 343.
Winkler J. Cited from Breidenbach 1935: Pilonidal Cysts and Sinuses". Wien Klin Wochenschr 1912; 25: 1348.
Breidenbach L, Wilson HL. Pilonidal Cysts and Sinuses. Ann Surg 1935; 102(3): 455-63.
McKirdie M. Pilonidal Sinus. Ann Surg 1938; 107(3): 389-99.
Kooistra HP. Pilonidal sinuses - review of literature and report of 350 cases. Am J Surg 1942; 55(1): 3-17.
Buie LA. Practical proctology. Philadelphia: Saunders, W. B.; 1937.
Johnson WJ, Livingston AG. The incidence of pilonidal sinuses in mental defectives. J Nerv & Ment Dis 1938; 87: 156-8.
Karydakis G. The problem of pilonidal cyst in the Greek Armed Forces (Greek). Hell Arm Forces Med Rev 1973; 7(4): 512-20.
Clark RL, Jr. The evolution of the treatment of pilonidal cysts and sinuses. J Indiana State Med Assoc 1946; 39: 387-92.
Pickett WJ, Beatty AJ. Pilonidal Cysts in the Army. Am J Surg 1942; 56(2): 375-8.
Pickett WJ, Beatty AJ. Pilonidal cysts in the army: A report of thirty cases occurring in ninety-seven days at Fort Sill, Oklahoma. Am J Surg 1942; 56(2): 375-8.
Favre R, Delacroix P. Apropos of 1.110 Cases of Pilonidal Disease of Coccy-Perineal Localization. Mem Acad Chir (Paris) 1964; 90: 669-76.
Parker HW. Pilonidal sinus: Its evaluation and treatment (A report of 500 cases). Am J Proctol 1951; 2(3): 111-20.
Dwight RW, Maloy JK. Pilonidal sinus; experience with 449 cases. N Engl J Med 1953; 249(23): 926-30.
Medicine USNSoN. Pilonidal cysts. 1956; 12: 3.
Franckowiak JJ, Jackman RJ. The etiology of pilonidal sinus. Dis Colon Rectum 1962; 5: 28-36.
Hopping RA. Pilonidal disease; review of the literature with comments on the etiology, differential diagnosis and treatment of the disease. Am J Surg 1954; 88(5): 780-8.
Davage ON. The Origin of Sacrococcygeal Pilonidal Sinuses: Based on an Analysis of Four Hundred Sixty-Three Cases. Am J Pathol 1954; 30(6): 1191-205.
Sebrechts PH. A significant diagnostic sign of pilonidal disease. DCR 1961; 4: 56-9.
Blackwell B, Rittelmeyer CM. Pilonidal sinus: a study of incidence and a review of literature. Bull Tulane Univ Med Fac 1959; 18: 141-56.
Powell KR, Cherry JD, Hougen TJ, Blinderman EE, Dunn MC. A prospective search for congenital dermal abnormalities of the craniospinal axis. congenital sinus dimple persisting 1975; 87(5): 744–50.
Campbell WB, Lee EJ, Van de Sijpe K, Gooding J, Cooper MJ. A 25-year study of emergency surgical admissions. Ann R Coll Surg Engl 2002; 84(4): 273-7.
Karydakis GE. Easy and successful treatment of pilonidal sinus after explanation of its causative process. ANZ J Surg 1992; 62(5): 385-9.
Obedman M, Vaticon D. Pilonidal sinus: a high-incidence disease among adolescents. Int J Adolesc Med Health 1993; 6(1): 21-36.
Hori T, Kan N, Hamagaki M. [Pilonidal disease in Japan; report of 4 cases and a review of the literature]. Nihon Geka Hokan 1984; 53(2): 437-46.
Nazarian PA. [Mass screening of adolescents with epithelial pilonidal cysts]. Sov Med 1987; (9): 72-6.
Vazquez BG, Alikhan A, Weaver AL, Wetter DA, Davis MD. Incidence of hidradenitis suppurativa and associated factors: a population-based study of Olmsted County, Minnesota. J Investig Dermatol 2013; 133(1): 97–103.
Sondenaa K, Andersen E, Nesvik I, Soreide JA. Patient characteristics and symptoms in chronic pilonidal sinus disease. Int J Colorectal Dis 1995; 10(1): 39-42.
Karydakis GE. Easy and successful treatment of pilonidal sinus after explanation of its causative process. ANZ J Surg 1992; 62(5): 385-9.
Yücesan S, Dindar H, Olcay I, et al. Prevalence of congenital abnormalities in Turkish school children. Eur J Epidemiol 1993; 9(4): 373-80.
Akinci OF, Bozer M, Uzunköy A, Düzgün SA, Coskun A. Incidence and aetiological factors in pilonidal sinus among Turkish soldiers. Eur J Surg 1999; 165(4): 339-42.
Carrasco L, Flores B, Aguayo JL, et al. Contribution of the outpatient surgery unit ITO the general surgery department of a district hospital. Amb Surg 2000; 8(3): 158.
Doll D, Luedi MM, Wieferich K, van der Zypen D, Maak M, Glanemann M. Stop insulting the patient: neither incidence nor recurrence in pilonidal sinus disease is linked to personal hygiene. PSJ 2015; 1(1): 11-9.
Armed Forces Health Surveillance C. Pilonidal cysts, active component, U.S. Armed Forces, 2000-2012. MSMR 2013; 20(12): 8-11.
Ardelt M, Dennler U, Fahrner R, et al. Puberty is a major factor in pilonidal sinus disease : Gender-specific investigations of case number development in Germany from 2007 until 2015. Chirurg 2017; 88(11): 961-7.
Doll D. Habilitationsschrift: Pilonidalsinus – Bestimmung der Rezidivrate und rezidivratenmodifizierender Faktoren. In: Universitäts-Klinik für Allgemein- V-uTmG, editor. Philipps-Universität zu Marburg; 2010.
Levinson T, Sela T, Chencinski S, et al. Pilonidal Sinus Disease: A 10-Year Review Reveals Occupational Risk Factors and the Superiority of the Minimal Surgery Trephine Technique. Mil Med 2016; 181(4): 389-94.
Sekmen Ü, Kara VM, Altintoprak F, Şenol Z. Pilonidal sinus in the army: Its incidence and risk factors. Turkish J Surg 2010; 26(2): 95-8.
Evers T, Doll D. Pilonidalsinus: Hohe chirurgische Rezidivrate. Amb Chir 2009; 6: 25-8.
Ardelt M, Dennler U, Fahrner R, et al. Adolescence is a major factor of sinus pilonidal disease - gender specific based investigation of case development in Germany from 2007 until 2015. Der Chirurg 2017.
Akbari Sari A, Babashahy S, Olyaeimanesh A, Rashidian A. Estimating the frequency and rate of first 50 common types of invasive procedures in iran healthcare system. Iranian Journal of Public Health 2012; 41(10): 60–4.
Aysan E, Ilhan M, Bektas H, et al. Prevalence of sacrococcygeal pilonidal sinus as a silent disease. Surg Today 2013; 43(11): 1286-9.
Nasr A, Ein SH. A pediatric surgeon's 35-year experience with pilonidal disease in a Canadian children's hospital. Can J Surg 2011; 54(1): 39-42.
Duman K, Girgin M, Harlak A. Prevalence of sacrococcygeal pilonidal disease in Turkey. Asian J Surg 2017; 40(6): 434-7.
Khodakaram K, Stark J, Hoglund I, Andersson RE. Minimal Excision and Primary Suture is a Cost-Efficient Definitive Treatment for Pilonidal Disease with Low Morbidity: A Population-Based Interventional and a Cross-Sectional Cohort Study. World J Surg 2017; 41(5): 1295-302.
Zímová J, Bačuvčíková H, Zímová P. Sinus pilonidalis sacrococcygealis. Prakt Lek 2015; 95(2): 73-6.
Spronk I, Korevaar JC, Poos R, et al. Calculating incidence rates and prevalence proportions: not as simple as it seems. BMC Public Health 2019; 19(1): 512.
Zu Erbach-Schoenberg E, Alegana VA, Sorichetta A, et al. Dynamic denominators: the impact of seasonally varying population numbers on disease incidence estimates. Popul Health Metr 2016; 14: 35.
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