Early and late Outcome, Mortality and major Morbidity after Lung Cancer Surgery for Primary Carcinoma.
AJTES Vol 2, No 2, July 2018
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Keywords

outcome
complications
lung cancer
thoracic surgery

How to Cite

Gradica, F., Lisha, L., Argjiri, D., Cani, A., Kokiqi, F., Gradica, F., Rexha, V., Lala, D., Xhemalaj, D., Vata, Y., Shpataraku, L., & Vyshka, A. (2018). Early and late Outcome, Mortality and major Morbidity after Lung Cancer Surgery for Primary Carcinoma. Albanian Journal of Trauma and Emergency Surgery, 2(2), 142-149. https://doi.org/10.32391/ajtes.v2i2.12

Abstract

Background: Radical surgical resection of lung cancer with or without adjuvant treatment is still a prerequisitefor cure. Advances in operative and postoperative care led to a decline in complications and mortality rates during the last decades. In spite of different additional modes of treatment, survival is still poor.
The aim of study: To examine the operative mortality and morbidity after lung cancer surgery and to identify factors associated with an adverse outcome.
Material and methods: The study comprised 968 consecutive patients referred to University Hospital of Lung Disease, “Shefqet Ndroqi” Tirana, Albania, for lung carcinoma, during a 13-years period (January 2004-December 2017). All patients underwent routine laboratory examinations spirometry and preoperative CT- scan of the thorax and upper abdomen. PET-CT, EBUS–EUS, Mediastinotomy or Mediastinoscopy wasn’t performed as routine.
Results: Of 968 patients, 690 (70.5%) were male and 278 (28.7%) female. Mean age 65.5±9.4 years (range 15 - 87 years). Lobectomy was the most used surgical modality in 566 (58.5%) patients, meanwhile pneumonectomy was performed in 112 (11.6%) of patients. Minor complications during surgery occurred in 45 (11.7%) ofpatients. Continuous air leakage was the most complication after surgery in 25.3%, followed by lung atelectasis in 21.3% and cardiovascular complications in 17%.
Conclusion: our results show low mortality and morbidity after lung cancer surgery. However, patients with reduced lung capacity, older age and those undergoing pneumonectomy should be treated with great care.

https://doi.org/10.32391/ajtes.v2i2.12
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References

Pastorino U, Yang XN, Massimo F, et al. Long-term survival after salvage surgery for invasive thymoma with intracardiac extension. Tumori 2008; 94: 772-6.

Solaini L, Prusciano F, Bagioni P, et al. Long-term results of video-assisted thoracic surgery lobectomy for stage I non-small cell lung cancer: a single-centre study of 104 cases. Interact Cardiovasc Thorac Surg 2004; 3: 57-62.

Imperatori A, Mariscalo G, Riganti G, et al. Atrial fibrillation after pulmonary lobectomy for lung cancer affects long-term survival in a prospective single-center study. J Cardiothorac Surg 2012; 7: 4.

Daly BD, Fernando HC, Ketchedjian A, et al. Pneumonectomy after high-dose radiation and concurrent chemotherapy for nonsmall cell lung cancer. Ann Thorac Surg 2006; 82: 227-31.

Inoue M, Okumura M, Minami M, et al. Cardiopulmonary co-morbidity: a critical negative prognostic predictor for pulmonary resection following preoperative chemotherapy and / or radiation therapy in lung cancer patients. Gen Thorac Cardiovasc Surg 2007; 55: 315-21

Lally BE, Detterbeck FC, Geiger AM, et al. The risk of death from heart disease in patients with nonsmall cell lung cancer who receivepostoperative radiotherapy: analysis of the Surveillance, Epidemiology, and End Results database. Cancer 2007; 110: 911-7.

Saha SP, Kalathiya RJ, Davenport DL, et al. Survival after pneumonectomy for stage III non-small cell lung cancer. Oman Med J 2014; 29: 24-7. Von Knorring J, Lepantalo M, Lindgren L, et al. Cardiac arrhythmias and myocardial ischemia after thoracotomy for lung cancer. Ann ThoracSurg 1992;53: 642-7.

Toker, A., Dilege, S., Ziyade, S. et al, Causes of death within 1 year of resection for lung cancer (Early mortality after resection) . Eur J Cardiothorac Surg. 2004; 25: 515–519.

Thomas P, Sielezneff I, Ragni J, et al. Is lung cancer resection justified in patients aged over 70 years? Eur J Cardiothorac Surg 1993; 7: 246-50;discussion 250-1.

Ploeg AJ, Kappetein AP, van Tongeren RB, et al. Factors associated with perioperative complications and long-term results after pulmonary resection for primary carcinoma of the lung. Eur J Cardiothorac Surg 2003; 23: 26-9.

Hollings DD, Higgins RSD, Faber Penfield L, et al. Age is a strong risk factor for atrial fibrillation after pulmonary lobectomy. Am J Surg 2010; 199: 558-61.

Kalathiya RJ, Saha SP. Pneumonectomy for non- small cell lung cancer:outcomes analysis. South Med J 2012; 105: 350-4.

Piehler JM, Trastek VF, Pairolero PC, et al. Concomitant cardiac and pulmonary operations. J Thorac Cardiovasc Surg 1985; 90: 662-7.

Canver CC, Bhayana JN, Lajos TZ, et al. Pulmonary resection combined with cardiac operations. Ann Thorac Surg 1990; 50: 796-9.

Adant JP, Defraigne JO, Limet R. Combined one stage cardiac and pulmonary surgery by median sternotomy. Acta Chir Belg 1990; 90: 97-202.

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