Non-surgical Treatment of Metastatic Liver Tumors with Microwave Ablation.
AJTES Vol 6, No 2, July 2022
Laçi I et al - Non-surgical Treatment of Metastatic Liver Tumors with Microwave Ablation.

Keywords

microwave
ablation
liver tumors
liver metastases

How to Cite

Laçi, I., & Spahiu, A. (2022). Non-surgical Treatment of Metastatic Liver Tumors with Microwave Ablation. Albanian Journal of Trauma and Emergency Surgery, 6(2), 1091-1096. https://doi.org/10.32391/ajtes.v6i2.289

Abstract

With all the measures taken, the trend of liver cancer cases has increased worldwide, as a consequence, this is accompanied by an increase in mortality by 43% (10.3 per 100,000 in 2016 (USA)) [1, 2].

Liver cancer is also associated with the lowest 5-year survival rate among all types of cancer (19%) [1].

Liver cancer (including intrahepatic bile duct cancer) was the ninth leading cause of cancer death in 2000 and rose to sixth in 2016 [3].

This shows that the identification of safe and effective treatments for liver cancer is urgent now.

Microwave ablation is a thermal ablation modality that has particular applicability in treating hepatic malignancies primary tumors or metastases. Microwaves can generate very high temperatures in short time periods, potentially leading to improved treatment efficiency in larger ablation zones.

We will show a patient male 55 years old. Post-surgery of colon cancer 6 months ago. Normal exam. There is e liver metastasis in the right lobe subcapsular 22mm. The patient was a good candidate for MWA.

Conclusions

MWA is an effective and safe alternative in patients/tumors that are not suitable for resection. Survival and recurrence outcomes after MWA are significantly improved with significantly shorter hospital stays and operative times, with little or no intraoperative blood loss and minor complications. Its use should be extended more and more in the field of treatment of these patients depending on the therapeutic indications

https://doi.org/10.32391/ajtes.v6i2.289
Laçi I et al - Non-surgical Treatment of Metastatic Liver Tumors with Microwave Ablation.

References

American Cancer Society. Cancer Facts & Figures 2018 [Available from: https://www.cancer.org/research/cancer-facts-statistics/all-cancer-facts-figures/cancer-facts-figures-2018.html.

Xu J. Trends in Liver Cancer Mortality Among Adults Aged 25 and Over in the United States, 2000-2016. NCHS Data Brief. 2018 Jul;(314):1-8. PMID: 30044212.

Hales CM, Carroll MD, Fryar CD, Ogden CL. Prevalence of obesity among adults and youth: United States, 2015–2016. NCHS Data brief, no 288. Hyattsville, MD: National Center for Health Statistics. 2017.

McGahan, J.P., van Raalte, V.A. (2005). History of Ablation. In: vanSonnenberg, E., McMullen, W.N., Solbiati, L., Livraghi, T., Müeller, P.R., Silverman, S.G. (eds) Tumor Ablation. Springer, New York, NY. https://doi.org/10.1007/0-387-28674-8_1

Adams F. Genuine works of Hippocrates. William Wood and Company; New York: 1886. translator. [Google Scholar] [Ref list]

D'Arsonval M. A. (1891). A. Referate I. Niederösterreich. Oesterr. Botan. Z. 41, 283–286. 10.1007/bf01790749 [CrossRef] [Google Scholar] [Ref list]

Clark WL. Oscillatory desiccation in the treatment of accessible malignant growths and minor surgical conditions. J Adv Ther. 1911;29:169–183. [Google Scholar] [Ref list]

Beer E. Landmark article May 28, 1910: Removal of neoplasms of the urinary bladder. By Edwin Beer. JAMA 1983; 250: 1324-1325. [PubMed] [Google Scholar] [Ref list]

Cushing H., Bovie W. T. (1928). Electro-surgery as an Aid to the Removal of Intracranial Tumors. Surg. Gynecol. Obstet. 47, 751–784.

Coley WB. The treatment of malignant tumors by repeated innoculations of erysipelas, with a report of ten original cases. Am J Med Sci. 1893;105:487–492. [Google Scholar] [Ref list]

Goldberg SN, Gazelle GS, Compton CC, McLoud TC (1995). Radiofrequency Tissue Ablation in the Rabbit Lung: Efficacy and Complications. Acad Radiol 2(9).

Dupuy DE, Zagoria RJ, Akerley W, Mayo-Smith WW, Kavanagh PV, Safran H (2000). Percutaneous radiofrequency ablation of malignancies in the lung. AJR Am J Roentgenol 174(1).

Dupuy DE (2009). Microwave Ablation Compared with Radiofrequency Ablation in Lung Tissue – Is Microwave Not Just for Popcorn Anymore? Radiology 251(3).

Lubner MG, Brace CL, Hinshaw JL, Lee FT Jr. Microwave tumor ablation: mechanism of action, clinical results, and devices. J Vasc Interv Radiol. 2010 Aug;21(8 Suppl): S192-203. doi: 10.1016/j.jvir.2010.04.007. PMID: 20656229; PMCID: PMC3065977.

Izzo F, Granata V, Grassi R, Fusco R, Palaia R, Delrio P, Carrafiello G, Azoulay D, Petrillo A, Curley SA. Radiofrequency Ablation and Microwave Ablation in Liver Tumors: An Update. Oncologist. 2019 Oct;24(10): e990-e1005. doi: 10.1634/theoncologist.2018-0337. Epub 2019 Jun 19. PMID: 31217342; PMCID: PMC6795153. C.J.

Simon, D.E. Dupuy, W.W. Mayo-Smith Microwave ablation: principles and applications Radiographics, 25 (October (Suppl. 1)) (2005), pp. S69-S83

C.L. Brace Radiofrequency and microwave ablation of the liver, lung, kidney, and bone: what are the differences? Curr Probl Diagn Radiol, 38 (May–June (3)) (2009), pp. 135-143

M. Tanaka, M. Sato Microwave heating of water, ice, and saline solution: molecular dynamics study J Chem Phys, 126 (January (3)) (2007), p. 034509

C.J. Simon, D.E. Dupuy, W.W. Mayo-Smith Microwave ablation: principles and applications Radiographics, 25 (October (Suppl. 1)) (2005), pp. S69-S83

Fallahi H, Prakash P. Antenna Designs for Microwave Tissue Ablation. Crit Rev Biomed Eng. 2018;46(6):495-521. doi: 10.1615/CritRevBiomedEng.2018028554. PMID: 30806212; PMCID: PMC6391890.

Conor J. Walsh, Alexander H. Slocum, and Rajiv Gupta "Preliminary evaluation of robotic needle distal tip repositioning", Proc. SPIE 7901, Energy-based Treatment of Tissue and Assessment VI, 790108 (22 February 2011); https://doi.org/10.1117/12.876604

Livraghi T, Solbiati L, Meloni MF, Gazelle GS, Halpern EF, Goldberg SN. Treatment of focal liver tumors with percutaneous radio-frequency ablation: complications encountered in a multicenter study. Radiology 2003; 226:441–451

Gervais DA, Goldberg SN, Brown DB, Soulen MC, Millward SF, Rajan DK. Society of Interventional Radiology position statement on percutaneous radiofrequency ablation for the treatment of liver tumors. J Vasc Interv Radiol 2009; 20(suppl 7):S342–S347

van der Sluis FJ, Bosch JL, Terkivatan T, de Man RA, Ijzermans JN, Hunink MG. Hepatocellular adenoma: cost-effectiveness of different treatment strategies. Radiology 2009; 252:737–746

Sharpe EE 3rd, Dodd GD 3rd. Percutaneous radiofrequency ablation of symptomatic giant hepatic cavernous hemangiomas: report of two cases and review of literature. J Vasc Interv Radiol 2012; 971–975

Hines-Peralta A U, Pirani N, Clegg P. et al. Microwave ablation: results with a 2.45-GHz applicator in ex vivo bovine and in vivo porcine liver. Radiology. 2006;239(1):94–102.

Shock S A, Meredith K, Warner T F. et al. Microwave ablation with loop antenna: in vivo porcine liver model. Radiology. 2004;231(1):143–149.

Lu M D, Xu H X, Xie X Y. et al. Percutaneous microwave and radiofrequency ablation for hepatocellular carcinoma: a retrospective comparative study. J Gastroenterol. 2005;40(11):1054–1060.

Schramm W, Yang D, Haemmerich D. Contribution of direct heating, thermal conduction and perfusion during radiofrequency and microwave ablation. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:5013–5016.

Trembly B S, Douple E B, Ryan T P, Hoopes P J. Effect of phase modulation on the temperature distribution of a microwave hyperthermia antenna array in vivo. Int J Hyperthermia. 1994;10(5):691–705.

Magin R L, Peterson A F. Noninvasive microwave phased arrays for local hyperthermia: a review. Int J Hyperthermia. 1989;5(4):429–450.

Clibbon K L, McCowen A, Hand J W. SAR distributions in interstitial microwave antenna arrays with a single dipole displacement. IEEE Trans Biomed Eng. 1993;40(9):925–932.

Camart J C, Dubois L, Fabre J J, Vanloot D, Chive M. 915 MHz microwave interstitial hyperthermia. Part II: Array of phase-monitored antennas. Int J Hyperthermia. 1993;9(3):445–454.

Durick N A, Laeseke P F, Broderick L S. et al. Microwave ablation with triaxial antennas tuned for lung: results in an in vivo porcine model. Radiology. 2008;247(1):80–87.

Glassberg MB, Ghosh S, Clymer JW, Wright GWJ, Ferko N, Amaral JF. Microwave ablation compared with hepatic resection for the treatment of hepatocellular carcinoma and liver metastases: a systematic review and meta-analysis. World J Surg Oncol. 2019 Jun 10;17(1):98. doi: 10.1186/s12957-019-1632-6. PMID: 31182102; PMCID: PMC6558848.

Stattner S, Jones RP, Yip VS, Buchanan K, Poston GJ, Malik HZ, et al. Microwave ablation with or without resection for colorectal liver metastases. Eur J Surg Oncol. 2013;39(8):844–849. doi: 10.1016/j.ejso.2013.04.005. [PubMed] [CrossRef] [Google Scholar] [Ref list]

Peek MCL, Douek M. Ablative techniques for the treatment of benign and malignant breast tumours. J Ther Ultrasound. 2017 Jul 3;5:18. doi: 10.1186/s40349-017-0097-8. PMID: 28680636; PMCID: PMC5494757.

Puijk, R.S., Ruarus, A.H., Vroomen, L.G.P.H. et al. Colorectal liver metastases: surgery versus thermal ablation (COLLISION) – a phase III single-blind prospective randomized controlled trial. BMC Cancer 18, 821 (2018). https://doi.org/10.1186/s12885-018-4716-8

Dupuy DE, Liu D, Hartfeil D, et al. Percutaneous radiofrequency ablation of painful osseous metastases: a multicenter American College of Radiology Imaging Network trial. Cancer 2010; 116:989–997

Thanou M, Gedroyc W. MRI-Guided Focused Ultrasound as a New Method of Drug Delivery. J Drug Deliv. 2013;2013:616197. doi: 10.1155/2013/616197. [PMC free article] [PubMed] [CrossRef] [Google Scholar] [Ref list]

Haar GT, Coussios C. High intensity focused ultrasound: physical principles and devices. Int J Hyperthermia. 2007;23(2):89–104. doi: 10.1080/02656730601186138. [PubMed] [CrossRef] [Google Scholar] [Ref list]

Li S, Wu PH. Magnetic resonance image-guided versus ultrasound-guided high-intensity focused ultrasound in the treatment of breast cancer. Chin J Cancer. 2013;32(8):441–452. doi: 10.5732/cjc.012.10104. [PMC free article] [PubMed] [CrossRef] [Google Scholar] [Ref list] Radiol 2012; 35:868–874.

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