Keywords
retroperitoneal
stromal tumor
CD117
How to Cite
Abstract
Introduction: Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors that can arise anywhere within the gastrointestinal tract. Approximately 70 % are in the Stomach, representing 1 – 3 % of all gastrointestinal malignancies. GISTs originate from the Cajal interstitial cells or their stem cell precursors within the myenteric plexus of the muscularis propria.
Histologically, GIST presents three different architectural patterns: a. composed of epitheloid cells embedded in a thin reticular stroma; b. by spindle cells with a fascicular or storiform arrangement immersed in a thin reticular stroma, focally myxoid, and c. the mixed form.
This study describes a 72-year-old man who, in computed tomography, presented a gross appearance of pancreatic cystic neoplasia. Clinicians should be aware that this condition might be mistaken for a primary pancreatic malignancy.
The diagnostic Workup includes endoscopy with ultrasonography, cross-sectional imaging studies, and histopathological examination.
Conclusions: The reported case illustrates that the retroperitoneum might be the place of initial presentation of a cystic gastric GIST and that only an accurate pathological evaluation can establish the diagnosis and origin. Clinicians must know that this condition might be mistaken for a primary pancreatic malignancy. Early surgical resection is the gold standard of treatment for primary GIST.
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