Keywords
Human herpes virus
HIV
Scrotal Kaposi
How to Cite
Abstract
Background: Kaposi's sarcoma (KS) is an indolent angio-proliferative tumor proliferation with spindle cells originating from endothelial and immune cells infected with human herpes virus type 8. (HHV-8: also known as Kaposi sarcoma herpes virus [KSHV]). HHV-8 was identified as the causative agent of KS. This virus is present in 95-98% of cases with KS. A Hungarian dermatologist named Moritz Kaposi first described Kaposi's sarcoma in 1872.[1]
The lesions are characterized by the proliferation of spindle cells of endothelial origin, which present different degrees of abnormal vascularization, inflammatory infiltrates, and fibrosis. Kaposi's Sarcoma (KS) is a malignancy that generally affects the skin and can be systemic with internal organ involvement. It originates from the vascular endothelium. KS's relationship with human immunodeficiency virus (HIV) infection is well known.
In this article, we will present a 73-year-old male patient with 3 purple scrotal lesions up to 0.5 cm in size.
Conclusion: Kaposi's sarcoma of the scrotum in a negative patient is a rare pathology. However, in cases of scrotal lesions that last over time, a differential diagnosis should be made, and Kaposi's sarcoma should be taken into consideration. Also, screening for other accompanying lesions, especially a detailed examination of the gastrointestinal tract, is important in cases of Kaposi’s sarcoma of the scrotum.
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