Pilonidal Sinus Carcinoma dying from Squamous Cell Carcinoma within 14 months after Diagnosis.
AJTES Vol 6, No 1, January 2022
Dettmer et al


Pilonidal Carcinoma
Pilonidal Sinus

How to Cite

Dettmer, M., Bonni, M., Degiannis, K., Maak, M., Doll, D., & Iesalnieks, I. (2022). Pilonidal Sinus Carcinoma dying from Squamous Cell Carcinoma within 14 months after Diagnosis. Albanian Journal of Trauma and Emergency Surgery, 6(1), 979 - 981. https://doi.org/10.32391/ajtes.v6i1.255


Introduction: The incidence of Pilonidal Sinus Disease (PSD) is increasing worldwide, especially in the developing and developed countries. As long-standing chronic infection may trigger neoplastic transformation, more carcinoma arising from PSD are to be expected with an incidence of 0,1%.

Methods: Case report describing a Squamous cell carcinoma (SCC) arising from PSD

Results: A 60-year-old male presented with a 6cm x 10cm ulcerating wound in the sacrococcygeal area, which was painful for 3 months. A biopsy initially revealed a highly differentiated squamous cell carcinoma (cT3cN1acM0G1). Soft tissue MRI showed possible infiltration of the coccyx, and a staging CT showed suspicious enlarged lymph nodes within both inguinal regions. The patient underwent a full 20x1,8 Gy chemoradiation with partial response of the primary. Surgical Resection was recommended. The patient did not show up for follow-up after chemoradiation and refused further treatment. He demised after 14 months due to pulmonary metastases.

Conclusion: Even a curative intended chemoradiation of this highly differentiated tumour led to a dismal outcome of disease after 14 months. Cases of PSD carcinomas often present as atypical cutaneous SCC.

Dettmer et al


Luedi, M.M., et al., Global Gender Differences in Pilonidal Sinus Disease: A Random-Effects Meta-Analysis. World J Surg, 2020. 44(11): p. 3702–3709.

Bosche, F., et al., The Hair in the Sinus: Sharp-Ended Rootless Head Hair Fragments can be Found in Large Amounts in Pilonidal Sinus Nests. World J Surg, 2018. 42(2): p. 567-573.

Doll, D., et al., The presence of occipital hair in the pilonidal sinus cavity-a triple approach to proof. Int J Colorectal Dis, 2018. 33(5): p. 567-576.

Downing, J.G., Barbers' pilonidal sinus. J Am Med Assoc, 1952. 148(17): p. 1501.

Dettmer, M., et al., Gender differences in axial hair strength may explain gender related incidence variation in Pilonidal Sinus patients. PSJ, 2021. 7(1): p. 11-20.

White, T.J., et al., Don't sit on chronic inflammation. ANZ J Surg, 2012. 82(3): p. 181-182.

Yuksel, M.E. and F. Tamer, All pilonidal sinus surgery specimens should be histopathologically evaluated in order to rule out malignancy. J Visc Surg, 2019. 156(5): p. 469-470.

Abboud, B. and H. Ingea, Recurrent squamous-cell carcinoma arising in sacrococcygeal pilonidal sinus tract: report of a case and review of the literature. DCR, 1999. 42(4): p. 525-528.

Kulaylat, M.N., M. Gong, and R.J. Doerr, Multimodality treatment of squamous cell carcinoma complicating pilonidal disease. Am Surg, 1996. 62(11): p. 922-929.

Mentes, O., M. Akbulut, and M. Bagci, Verrucous carcinoma (Buschke-Lowenstein) arising in a sacrococcygeal pilonidal sinus tract: report of a case. Langenbecks Arch Surg, 2008. 393(1): p. 111-114.

Al-Zacko, S.M., Malignancy in chronic burn scar: a 20 year experience in Mosul-Iraq. Burns, 2013. 39(7): p. 1488-91.

Silberstein, E., et al., Lymph Node Metastasis in Cutaneous Head and Neck Squamous Cell Carcinoma. Dermatol Surg, 2015. 41(10): p. 1126-9.

Shen, R., et al., Clinical characteristics and therapeutic analysis of 51 patients with Marjolin's ulcers. Exp Ther Med, 2015. 10(4): p. 1364-1374.

Borges, V.F., et al., Clinicopathologic characterization of squamous-cell carcinoma arising from pilonidal disease in association with condylomata acuminatum in HIV-infected patients: report of two cases. DCR, 2001. 44(12): p. 1873-1877.

Hollestein, L.M., E. de Vries, and T. Nijsten, Trends of cutaneous squamous cell carcinoma in the Netherlands: increased incidence rates, but stable relative survival and mortality 1989-2008. Eur J Cancer, 2012. 48(13): p. 2046-53.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.